Further understanding the genetics of dementia with Lewy bodies

Using the expertise gained in identifying genetic risk factors for Alzheimer’s disease, we will now investigate the genetic factors that contribute to the risk of developing dementia with Lewy bodies (DLB), an often overlooked and under-researched type of dementia. Building on our strong links with over 60 NHS trusts/health boards across the UK who make up the NHS Clinical Research Network, we will deeply phenotype and collect biological samples on 750 DLB patients. Developing this research ready cohort will help us to understand the genetic factors that contribute to DLB, which will aid future progress in DLB diagnosis and treatment.

Collaboration

To identify and recruit participants for this study requires close collaboration with NHS Health boards and trusts across Wales, England and Scotland.

Highlights

  • Dissemination of findings through public engagement events.
  • Banking of 750 DLB biological samples and rich phenotypic data.
  • Providing a valuable store of biological samples for future research.
  • Identification of common genetic variants that contribute to DLB.

 

We are inviting people who have received a diagnosis of Lewy body dementia to help with this research. If you would like more information about our research or are interested in taking part, you can contact the Cardiff University Dementia Research team on 02920 688042 or via email at ADresearch@cardiff.ac.uk 

 

For information on our past research please click these links: 

Further Understanding the Genetics of Alzheimer's Disease

Translation of Genetic findings into clinical and social impact

CRISPR/Cas9 Genome Editing to Model AD Risk Variants with Isogenic Pluripotent Stems Cells